图9-13 抗Id(4D6)治B细胞瘤示意图 (金伯泉 许辉) 参 考 文 献 1.Bhattacharya-Chatterjee M,et al.Idiotype vaccines against human T cell leukemi-a.II. Generation and characterizization of a monoclonal idiotype cascade (Ab1,Ab2 and Ab3).J Immunol,1988;141:1398 2.Bhattacharya-Chatterjee M,et al.Idiotype vaccines against human T cell acute lymphoblastic leukemia(T-ALL).I. Generation and characterization of biologically active monoclonal anti-idiotypes.j Immunol,1987;139:1354 3.Bhattachary-Chatterjee M,et al.Murine monoclonal anti-idiotype antibody as a potential network antigen for human carcino-embryonic antigen.j Immunol,1990;140:2758 4.Bhattacharya-Catterjee MB et al.Idiotypic antibody immunotherapy of cancer.Cancer Immunol Immunother 1994;38:75 5.Chattopadhyay P,et al.Murine monoclonal anti-idiotype antibody breaks unresponsiveness and induces a specific antibody response to human melanoma-associated proteoglycan antigen in cynomolgus.Proc Natl Acal Sci USA,1992;89:2684 6.Davie JM,et al.Structrual correlates of idiotopes.Ann.Ren.Immunol.1986:4:147 7.Grzych JM,et al.An anti-idiotype vaccine against experimental schistosomiasis.Nature,1985;316:74 8.Herlyn D,et al.Anti-idiotype immunization of cancer patients:modulation of the immune response.Proc Natl Acad Sci USA,1987;84:8055 9.Herlyn D,et al.Anti-idiotype antibodies bear the internal image of a human tumor antigen.Science,1986;232:101 10.Jerne NK,et al.Recurrent idiotypes and internal image.EMBO j 1982;1:243 11.Jerme NK.Towards a network theory of the immune systim .Ann Immunol(Paris),1974;125C:373 12.Kennedy RC,et al.Anti-idiotypic antibody vaccine for type B viral hepatitis in chimpanzees.Science,1986;232:220 13.McNamara MK,et al.Monoclonal idiotype vaccine against Strcptococcus pneumoniae infection.Scicnce,1984;226:1325 14.Mittelman A,et al.Human high molecular weight melanoma-associated antigen(HMW-MAA)mimicry by mouse anti-idiotypic monoclonal antibody MK2-23:induc-tion of humoral anti-HMW-MAA immunity and prolongation of survival in patients with stage IV melanoma.Proc Natl Acad Sci USA,1992;89:466 15.Nisonoff A and Lamoyi E.Impllications of the presence of an internal image of the antigen anti-idiotypic antibodies:possible application to vaccine production.Clin Immunol Immunopathol,1981;21:397 16.Rodkey LS.Autoregulation of immune response via idiotype network interactions .Microbiol Rev 1980;44:631 17.Roitt IM.Encyclopedia of Immunology.lst ed .San Diego:Academic Press ine .1992:723 18.Roitt IM.Essential Immunology.6th ed.Oxford:Blackwell Scientific publications.1988;P35-37,P121-125 19.Roitt IM.et al.Idiotypic networks and their possiblse exploitation for manipulation of the immune response.Lancet,1981;I:1041 20.Sacks DL.et al.Immunization of mice against African trypanosomiasis using antiidiotypic antibobies.J Exp Med,1982;155:1108 21.Sharpe AH,et al.Syngeneic monoclonal anti-idiotype can induce cellular immunity to reovirus.J Exp Med,1984;160:1195 22.Stein KE and Sderstrom J.Neonatal administration of idiotype or anti-idiotype primes for protection against Escherichia coli K13 infection in mice.J Exp Med,1984;160:1001 23.Uytdehaag IGCM and Osterhaus ADME.Induction of meutralizing antibody in mice against poliovirus type II with monoclonal anti-idiotype antibody.J Immunol,1985;134:1225 24.Victor-Kobrin,et al.Structural correlates of a regulatory idiotope.1989;Immunol Rev 110:151 25.Wasserman NH,et al.Anti-idiotypic route to anti-acetyecholine receptor antibodies and experimental myasthinia gravis.Proc.Natl.Acad Sci USA,1982,79(15):4810 26.陈敬贤、马宝骊.抗体的独特型与免疫网络研究进展.国外医学免疫学分册,1987;5:238 (责任编辑:泉水) |