NAME:                Guang-Yin Xu, M.D., Ph. D.

PRESENT POSTION AND ADDRESS:

1. Plasticity of P2X receptor in chronic visceral hyperalgesia. National Institute of Diabetes & Digestive & Kidney Diseases Principal Investigator (30% effort): Guang-Yin Xu; Co-investigator: Pankaj Jay Pasricha; Funding: Pending.

2. Mechanisms of sensitization in a rat model of chronic visceral hypersensitivity. National Institute of Diabetes & Digestive & Kidney Diseases Principal Investigator: Dr. John Winston; Co-investigator (20% effort): Guang-Yin Xu; Funding: Pending.
3. Molecular Mechanisms of Pain in Chronic Pancreatitis”.  National Institute of Diabetes & Digestive & Kidney Diseases R01. $1,819,550.00/4yrs. Principal Investigator: Pankaj Jay Pasricha; Co-investigator (50% effort): Guang-Yin Xu; Funding: funded.  This proposal examines the hypothesis that the pathogenesis of pain in chronic pancreatitis involves changes in pancreas-specific sensory neuronal excitability and neurotransmitter expression/release and that such changes are mediated, at least in part, by nerve growth factor (NGF) expressed in pancreatic tissue. The goals of this project are to determine the ionic and molecular basis for increased excitability of pancreas-specific primary nociceptive neurons in chronic pancreatitis, to determine the effects of chronic pancreatitis on expression and release of peptide neurotransmitters and their role in maintaining nociceptive sensitization and to determine the role of NGF in the pathogenesis of pain behavior and pancreas-specific sensory neuronal responses in chronic pancreatitis.  Guang-Yin will perform pancreas-specific sensory neuron excitability and ion channel activity experiments.
4. 1996-1998, Co-Principal Investigator in research project entitled “The role of IL-2 in Pain Modulation”, Research foundation of National Nature Science Foundation of China.

5. 1993-1995, Director and Principal Investigator in research project entitled “The Critical Role of SN in Electroacupuncter Analgesia in Adjuvant Arthritic Rats”, Research foundation of Nantong University Medical School.

1. The first prize awarded by Education Department in China, 2004
2. The Award Winner for the oral presentation at the 7th annual UTMB-CSA life science symposium.  Galveston, Texas, 2003.
3. The traveling Award from the International Congress of Phsyiological Science, 1997
4. The first prize awarded by president of Chinese Academy of Sciences, 1997.
5. The third prize awarded by the Chinese Society for Neuroscience, 1997.
6. The third prize awarded by the Association of Science and Technology of Nantong, Jiangsu province, P. R. China,  1995.

7. The third prize awarded by Chairman of Academic Committee of Nantong Medical College, 1993.

8. The fourth prize awarded by Chairman of Academic Committee of Nantong Medical College. 1993.
9. The third prize awarded by the Department of Basic Medicine of Nantong Medical College, 1993.
10. The first prize awarded by the president of Suzhou Medical College, 1993.

1. The 35th Annual Meeting of the Society for Neuroscience, Atlanta, GA, Oct. 14-18, 2006
2. Neurogastroenterology and Motility 2006 first Joint International Meeting in Boston, MA, September 13-16, 2006
3. The 4th International Neuroscience Symposium in China, Kunming, P.R. China, July 1-8, 2006
4. Digestive Disease Week and the 107th Annual Meeting of American Gastroenterological Association, Los Angelus, CA, May 13-18, 2006
5. The 34th Annual Meeting of the Society for Neuroscience, Washington DC, Nov. 12-16, 2005
6. Gulf Coast GI Research Forum, June 4, 2005, League City, Texas.
7. The 106th Annual Meeting of the American Gastroenterological Association, May 14-18, 2005, Chicago, IL
8. The 7th annual UTMB-CSA Life Science Symposium.  Galveston, Texas, May 23, 2003.
9. The thirty-one Annual Meeting of Society for Neuroscience, Orlando, USA, Nov., 2002.

10. The thirty-one Annual Meeting of Society for Neuroscience, San Diego, USA, Nov., 2001.

11. Neuroscience Graduate Program Poster Session for BBSC Orientation (BBSC 6105), Levin Hall, UTMB, Oct. 16, 2001.
12. The 5th Annual Life Science Symposium. Levin Hall, UTMB, May, 2001.
13. The 30th Annual Meeting of Society for Neuroscience, New Orleans, USA, Oct., 2000.
14. Forum on Neuroscience, the University of Texas Medical Branch. William C. Levin Hall, Feb., 2000
(责任编辑：泉水)