王佐仁(Zuoren Wang)

Curriculum Vitae
Name: Zuoren Wang
Address: 291 Life Science Addition Department of Molecular and Cell Biology University of California at Berkeley Berkely, CA 94720-3200 Phone: (510) 643-4152 Fax: (510) 642-4154 Email: zrwang@uclink.berkeley.edu

Education: Ph.D. in Biochemistry (2001) Rutgers--the State University of New Jersey New Brunswick/Piscataway, New Jersey, USA

M.S. in Biochemistry (1997) Shanghai Institute of Biochemistry Chinese Academy of Science Shanghai, China

B.S. in Biochemistry (1994) East China University of Science and Technology Shanghai, China

Research Experience:
Post-doctoral Advisor: Kristin Scott, Ph.D. Aug. 2003--present Department of Molecular and Cell Biology Helen Wills Neuroscience Institute University of California at Berkeley Berkeley, California Research topic: Neural Circuits underlying Drosophila Taste Discrimination.

Post-doctoral Advisor: Mu-ming Poo, Ph.D. May 2002—July 2003 Department of Molecular and Cell Biology University of California at Berkeley Berkeley, California Research topic: Molecular Mechanism of Synaptic Plasticity.

Graduate Advisor: Megerditch Kiledjian, Ph.D. Sept. 1997—Apr. 2002 Department of Cell Biology and Neuroscience

Rutgers--the State University of New Jersey Piscataway, New Jersey Research topic: Post-transcriptional Control of Mammalian Gene Expression on the mRNA Turnover Level.

Graduate Advisor: Shangquan Zhu, Prof. Sept. 1994--July 1997 Shanghai Institute of Biochemistry Chinese Academy of Science Shanghai, China Research topic: Genetic Engineering of Human Glucagon.

Undergraduate Advisor: Yuancong Zhou, Prof. Sept. 1993--July 1994 Shanghai Institute of Biochemistry Chinese Academy of Science Shanghai, China Research topic: Purification and Functional Analysis of Enzymes from Snake Venom.

Honors and Awards:
2000 Anne B. and James R. Leathem Research Fellowship Rutgers--the State University of New Jersey

Publications:

Wang, Z., Chen, J., Wu, W., Feng, Bo., and Zhou Y. (1996). Purification and Biochemical Characterization of the Platelet Aggregation Factor from the Trimeresurus Stejnegeri Schmidt Venom. Chinese Biochemical Journal 12:303-307.

Wang, Z., Day, N., Trifillis, P. and Kiledjian, M. (1999). An mRNA Stability Complex Functions with the Poly(A)-Binding Protein to Stabilize mRNA In Vitro. Mol. Cell. Biol. 19:4552-4560.

Wang, Z., and Kiledjian, M. (2000). Identification of an Erythroid-Enriched Endoribonuclease Activity Involved in Specific mRNA Cleavage. EMBO J. 19:295-305.

Wang, Z., and Kiledjian, M. (2000). The Poly(A)-Binding Protein and an mRNA Stability Protein Jointly Regulate an Endoribonuclease Activity. Mol. Cell. Biol. 20:6334-6341.

Barnhart, B., .Kosinski, P., Wang, Z., Ford, G.S., Kiledjian, M. and Covey, L.R. (2000). Identification of a Complex that binds to the CD154 3´UTR: Implications for a Role in Message Stability during T cell Activation. J. Immunology. 165:4478-4486.

Wen C., Wang Z., Du P., Gan R., and Zhu S. (2001). Secretion expression of recombinant glucagon in Escherichia coli. Science in China Series C. 4:233-240.

Wang, Z., and Kiledjian, M. (2001). Functional Link between the Mammalian Exosome and mRNA Decapping. Cell. 107:751-762.

Rodgers, N., Wang, Z., and Kiledjian, M. (2002). Characterization and Purification of a Mammalian Endoribonuclease Specific for the α-Globin mRNA. J. Biol. Chem. 277:2597-2604.

Wang, Z.*, Jiao, X*., Carr-Schmid*, A. and Kiledjian, M. (2002). Dcp2 Protein is a Regulated Mammalian mRNA Decapping Enzyme. Proc. Natl. Acad. Sci. USA. 99:12663-12668.

Rodgers, N.D., Wang, Z. and Kiledjian, M. (2002). Regulated α-globin mRNA decay is a cytoplasmic event proceeding through 3' to 5' exosome-dependent decapping. RNA. 8:1526-1537.

Wang, Z., Singhvi, A., Kong, P., Scott, K. (2004). Taste representations in the Drosophila brain. Cell. 117:981-991.

Zhou, Q.*, Wang, Z.*, Wong, S., Tao, H.W., and Poo M.M. (2003). TrkB Receptor Signaling is Essential for LTP and Receptive Field Refinement in a Developing Retinotectal System. Submitted.

References:

Kristin Scott, Ph.D. Assistant Professor, Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720-3200

Megerditch Kiledjian, Ph.D. Associate Professor Department of Cell Biology and Neuroscience, Rutgers--the State University of New Jersey Piscataway, New Jersey 08854

Lori Covey, Ph.D. Associate Professor Department of Cell Biology and Neuroscience, Rutgers--the State University of New Jersey Piscataway, New Jersey 08854

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王佐仁(Zuoren Wang)